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ea0099p516 | Pituitary and Neuroendocrinology | ECE2024

Cytokeratin 18: An early biomarker of increased liver fibrosis in newly diagnosed acromegaly

Coskun Meric , Nahit Sendur Halit , Babayeva Afruz , Nur Cerit Mahi , Turgay Cerit Ethem , Muhittin yalcin Mehmet , Eroglu Altinova Alev , Akturk Mujde , Ayhan Karakoc Mehmet , Balos Toruner Fusun

Purpose: The liver is known to be protected from steatosis under the influence of high GH/IGF-1. Cytokeratin 18 (CK18) and insulin-like growth factor binding protein 7 (IGFBP7) increase in liver steatosis and fibrosis. Whether decreasing lipid content completely protects the liver from metabolic alterations and the response of CK18 and IGFBP7 to liver changes in acromegaly is unknown.Methods: This single-center, multidisciplinary, cross-sectional study i...

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ea0090rc7.5 | Rapid Communications 7: Pituitary and Neuroendocrinology 2 | ECE2023

Evaluation and follow-up data of patients diagnosed with hypophysitis: A multicentric nationwide study

Hacioglu Aysa , Karaca Zuleyha , Uysal Serhat , Ozkaya Hande Mefkure , Kadioglu Pinar , Selcukbiricik Ozlem Soyluk , Yarman Sema , Gul Nurdan , Koksalan Damla , Selek Alev , Cetinarslan Berrin , Canturk Zeynep , Tuğce Şah unal Fatma , Corapcıoğlu Demet , Sahin Mustafa , Babayeva Afruz , Akturk Mujde , Eraydin Ayten , Fenkci Semin , Piskinpasa Hamide , Ciftci Sema , Dokmetaş Meric , Şahin Onur , Sebile Dokmetas H. , Ozturk Sadettin , Akarsu Ersin , Kılıc Kan Elif , Atmaca Aysegul , Pehlivan Esma , Saygili Fusun , Erkan Buruc , Burhan Sebnem , Omma Tulay , Uc Ziynet Alphan , Elbuken Gulsah , Bayram Fahri , Yorulmaz Goknur , Cansu Guven Baris , Bostan Hayri , Turan Kubra , Sener Selcuk Yusuf , Gorar Suheyla , Pekkolay Zafer , Hekimsoy Zeliha , Dogruel Hakan , Ertorer Melek Eda , Topaloğlu Omercan , Celik Ozlem , Iyidir Ozlem , Kelestimur Fahrettin

Background: Hypophysitis is a rare group of disease characterized with infla mmation of the pituitary gland. Rarity of the disease obviates development of a treatment strategy. We aimed to present the nationwide data of the demographics, clinical and radiological characteristics, treatment modalities and responses of the patients diagnosed with hypophysitis in a retrospective manner.Methods: The endocrinology clinics all over the country were invited to ...

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Endocrine Abstracts

Cytokeratin 18: An early biomarker of increased liver fibrosis in newly diagnosed acromegaly

Evaluation and follow-up data of patients diagnosed with hypophysitis: A multicentric nationwide study

BiosciAbstracts